The Mechanism of Action

Tamiflu is a prodrug. This means that the drug has to be activated after it is ingested before it can do its job. It works as a competitive inhibitor of the neuraminidase enzyme on the virus. This prevents virus from transporting its genetic information into the host’s cell once the virus has come into contact with host cell’s glycoproteins. By preventing the transfer of the viruses genetic material into the host cell, the virus is indirectly inhibited from replicating. This is due to the fact that the virus needs to utilize the host cell’s replication materials for the virus to be able to replicate.

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